Degradación enzimática de TRH y análogos en semen humano. Posible función en la fertilidad

FERNÁNDEZ OSORIO, David
; GIL GOIKOURIA, Javier
; IRAZUSTA ASTIAZARAN, Jon
; LARRINAGA ENBEITA, Gorka
; MUJIKA GARAY, Juan
; OCHOA, Carmen

Publication year:

2001

Publication place:

Donostia-San Sebastián

ISSN:

1577-8533

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Summary

Recently it has been described the presence in human semen of a thyrotropin-releasing hormone (TRH) like peptide, directly implicated in the fertility and therefore it has been called fertilization promoting peptide (FPP). We have measured the activities of the most important peptidases in the degradation of these peptides in semen in different diagnostics. Although there are significative differences among the diagnostics, these variations are not clear enough to accept these peptidases like valid markers.